Intravenous immunoglobulin for neonatal isoimmune thrombocytopenia.

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Intravenous immunoglobulin for neonatal isoimmune

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Maternal platelet antibody levels in neonatal isoimmune thrombocytopenia.

A case of neonatal isoimmune thrombocytopenia (NIT) is described in which maternal platelet antibody levels decreased during the course of pregnancy. It is suggested that if this disorder is clinically suspected, maternal serum should be assessed for anti-platelet specificity using immunoblot analysis.

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Porencephaly and optic hypoplasia in neonatal isoimmune thrombocytopenia.

Five children with prenatal intracerebral damage associated with neonatal isoimmune thrombocytopenic purpura are described, and characteristic neurological features listed. These include optic hypoplasia which has not been previously documented in this condition.

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Isoimmune neonatal thrombocytopenic purpura.

Ten cases of isoimmune neonatal thrombocytopenic purpura (4 pairs of siblings and 2 singletons) are described. The condition was diagnosed by excluding other causes of thrombocytopenia , and in 8 cases it was confirmed by detecting antiplatelet antibodies in the mother. Perhaps steroids should be given to affected infants as soon as the condition is diagnosed in order to stabilise the capillary...

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Fetal alloimmune thrombocytopenia and maternal intravenous immunoglobulin infusion.

BACKGROUND Different therapeutic approaches have been used in fetal-neonatal alloimmune thrombocytopenia, but many centers administer immunoglobulin G infusions to the pregnant woman. We studied the effect of maternal antenatal immunoglobulin infusions on fetal platelet counts in pregnancies with fetal alloimmune thrombocytopenia. DESIGN AND METHODS We retrospectively analyzed the clinical co...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 1985

ISSN: 0003-9888,1468-2044

DOI: 10.1136/adc.60.7.667